Thermo Fisher Scientific EPB41L2/4.1G Polyclonal Antibody
Thermo Fisher Scientific의 EPB41L2/4.1G Polyclonal Antibody는 인간 단백질 4.1G를 인식하는 토끼 유래 IgG 항체입니다. Western blot과 Immunoprecipitation에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로 사용되며, 4°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 575 and 625 of human erythrocyte membrane protein band 4.1-like 2 (Generally expressed protein 4.1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
The 4.1 gene family encodes a group of multifunctional cytoskeletal proteins (4.1R, 4.1G, 4.1N, and 4.1B), predominantly expressed in the nervous system.
4.1G stabilizes spectrin-actin interactions and is associated with hereditary elliptocytosis.
4.1R is essential for maintaining erythrocyte shape and membrane mechanical properties.
Both 4.1R and 4.1G are distributed uniquely in the cerebellum and modulate neuronal membrane mechanics by promoting fodrin/actin association.
4.1N (EPB41L1) and 4.1B (EPB41L3) are strongly expressed in the brain.
Antibodies to 4.1N detect multiple forms enriched in postsynaptic density, while antibodies to 4.1B detect two forms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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