Thermo Fisher Scientific MAPK1/ERK2 (Transcription Factor) Monoclonal Antibody (PCRP-MAPK1-1D1)
인간 MAPK1/ERK2를 인식하는 단일클론 항체로, ICC/IF, Flow, ELISA, IP 등 다양한 응용에 사용 가능. 단백질 A/G로 정제된 액상 형태이며, 보존제가 없는 PBS 용액에 제공. 연구용으로만 사용.
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Thermo Fisher Scientific MAPK1/ERK2 (Transcription Factor) Monoclonal Antibody (PCRP-MAPK1-1D1)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.5–2 µg/mL |
| Flow Cytometry (Flow) | 0.5–2 µg/10⁶ cells |
| ELISA | Assay-dependent |
| Immunoprecipitation (IP) | 1–2 µg/100–500 µg total protein |
| Peptide Array | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | PCRP-MAPK1-1D1 |
| Immunogen | Recombinant full-length human MAPK1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
MAPK1 (ERK2) is a serine/threonine kinase that acts as an important activator of p90 RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of stimulated cells, where it phosphorylates nuclear targets.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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