Thermo Fisher Scientific Aromatase/Cytochrome P450 (CYP19A1) Monoclonal Antibody (CYP19A1/4257)
인체 Aromatase/Cytochrome P450 (CYP19A1)을 인식하는 mouse monoclonal 항체입니다. Western blot, IHC(P), IHC(PFA), ELISA에 사용 가능하며, Protein A/G로 정제된 1 mg/mL 액상 형태입니다. PBS(pH 7.4)에 보존되며, -20°C에서 보관합니다.
- 카탈로그번호
- 1588-MSM1-P1ABX
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1–2 µg/mL | |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL | |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Details |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CYP19A1/4257 |
| Immunogen | Synthetic peptide corresponding to aa376–390 of human aromatase (KALEDDVIGYPVKK) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and the synthesis of cholesterol, steroids, and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the final steps of estrogen biosynthesis through three successive hydroxylations of the A ring of androgens. Mutations in this gene can lead to altered aromatase activity, affecting estrogen-related physiological functions. Two transcript variants have been identified for this gene.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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