Thermo Fisher Scientific LAGE3 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human LAGE3. Recombinant protein control fragment (Product #RP-95192). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LAGE3,uniProtId:Q14657-1,ncbiNodeId:9606,antigenRange:62-138,antigenLength:143,antigenImageFileName:PA5-57526_LAGE3_Q14657-1_Rabbit.svg,antigenImageFileNamePDP:PA5-57526_LAGE3_Q14657-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2643253

Product Specific Information

Immunogen sequence: IFTLSVPFPT PLEAEIAHGS LAPDAEPHQR VVGKDLTVSG RILVVRWKAE DCRLLRISVI NFLDQLSLVV RTMQRFG

Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 71%.

Target Information

This gene belongs to the ESO/LAGE gene family, members of which are clustered together on chromosome Xq28, and have similar exon-intron structures. Unlike the other family members which are normally expressed only in testis and activated in a wide range of human tumors, this gene is ubiquitously expressed in somatic tissues. The latter, combined with the finding that it is highly conserved in mouse and rat, suggests that the encoded protein is functionally important. An intronless pseudogene with high sequence similarity to this gene is located on chromosome 9.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.