Thermo Fisher Scientific PSMB7 Monoclonal Antibody (OTI4E3), TrueMAB
PSMB7 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI4E3). WB, ICC/IF에 사용 가능하며, Human, Mouse, Rat, Dog에 반응. 0.83 mg/mL 농도의 액상 제품으로 -20°C 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4E3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 58–277 of human PSMB7 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.83 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure composed of four rings of 28 non-identical subunits: two rings of seven alpha subunits and two rings of seven beta subunits. Proteasomes are distributed throughout eukaryotic cells at high concentrations and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.
A modified proteasome, the immunoproteasome, processes class I MHC peptides.
The gene encodes a member of the proteasome B-type (T1B) family, a 20S core beta subunit. Expression of this catalytic subunit is downregulated by gamma interferon, and proteolytic processing is required to generate a mature subunit. This subunit is not present in the immunoproteasome and is replaced by catalytic subunit 2i (proteasome beta 10 subunit).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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