Thermo Fisher Scientific RAB21 Polyclonal Antibody

Applications

• Western Blot (WB): 1:2,000–1:10,000
• Immunoprecipitation (IP): 2–10 µg/mg lysate

Product Specifications

Product Specific Information

The recommended shelf life for this product is 1 year from the date of receipt.

Target Information

RAB21 is a member of the small GTP-binding Ras superfamily involved in intracellular vesicular trafficking.
In non-polarized Caco-2 cells, RAB21 shows ER-like localization, whereas in polarized cells, it localizes to apical vesicles.
RAB21 associates with integrin subunits and facilitates receptor entry into cells via RAB5/RAB21 endosomes.
The GTPase-activating protein p120RasGAP regulates cell motility by controlling the recycling of endocytosed integrins through competition with RAB21 for binding to overlapping sites on the α-tail of integrin.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.