Thermo Fisher Scientific RAB21 Polyclonal Antibody
RAB21 단백질을 인식하는 Rabbit Polyclonal 항체로, Western Blot 및 Immunoprecipitation에 적합합니다. 인간 및 생쥐 시료에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. 4°C에서 보관하며 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:2,000–1:10,000
- Immunoprecipitation (IP): 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 172–222 of Human Ras-related protein Rab-21 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from the date of receipt.
Target Information
RAB21 is a member of the small GTP-binding Ras superfamily involved in intracellular vesicular trafficking.
In non-polarized Caco-2 cells, RAB21 shows ER-like localization, whereas in polarized cells, it localizes to apical vesicles.
RAB21 associates with integrin subunits and facilitates receptor entry into cells via RAB5/RAB21 endosomes.
The GTPase-activating protein p120RasGAP regulates cell motility by controlling the recycling of endocytosed integrins through competition with RAB21 for binding to overlapping sites on the α-tail of integrin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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