Thermo Fisher Scientific Human Factor V Native Protein

Applications

• Control (Assay-dependent)

Product Specifications

Product Specific Information

RP-43126 contains native human Factor V protein.
RP-43126 may be used as a positive control in many immunological assays.
The product is of human blood/plasma origin. Although the starting material was tested prior to initiation of the manufacturing process and found negative or nonreactive for anti-HIV-1/2, HIV-1 antigen(s), HBsAg, STS, anti-HCV, anti-HBcore, and anti-HTLV I & II, extreme caution should be used when handling this material as there is a margin of error in all tests.
This product is to be used for in vitro research purposes only, and is not intended for clinical or diagnostic use.

Target Information

Coagulation factor V (or Proaccelerin) is an essential factor of the blood coagulation cascade. This factor circulates in plasma and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain held together by calcium ions. The active factor V acts as a cofactor with activated coagulation factor X to activate prothrombin to thrombin.
Defects in the Factor V gene can result in various diseases including Factor V deficiency, thrombophilia due to activated protein C resistance, Budd-Chiari syndrome, ischemic stroke, and recurrent pregnancy loss.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.