Thermo Fisher Scientific DCAF7 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:50

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human DCAF7. Recombinant protein control fragment (Product #RP-93331). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DCAF7,uniProtId:P61962-1,ncbiNodeId:9606,antigenRange:84-169,antigenLength:342,antigenImageFileName:PA5-54647_DCAF7_P61962-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54647_DCAF7_P61962-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2640410

Product Specific Information

Immunogen sequence: YPDLLATSGD YLRVWRVGET ETRLECLLNN NKNSDFCAPL TSFDWNEVDP YLLGTSSIDT TCTIWGLETG QVLGRVNLVS GHVKTQ

Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

Target Information

WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WDR68 (WD repeat-containing protein 68), also known as DCAF7 (DDB1- and CUL4- associated factor 7), HAN11 or WDR68, is a 342 amino acid protein that belongs to the WD repeat DCAF7 family and contains 4 WD repeats. Localizing to the cytoplasm and nucleus, WDR68 is involved in protein modification and ubiquitination pathways, and interacts directly with Dyrk1A, Dyrk1B and Dia 1. WDR68 is involved in craniofacial development, and may be involved in skin development.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.