Thermo Fisher Scientific RRP4 Polyclonal Antibody
Thermo Fisher Scientific의 RRP4 Polyclonal Antibody는 인간 RRP4 단백질을 인식하는 토끼 유래 IgG 항체로, Western blot, IHC, ICC/IF에 적합합니다. RNA exosome 복합체 연구에 사용되며, 고순도 항원 친화 크로마토그래피로 정제된 액상 형태입니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific RRP4 Polyclonal Antibody
Thermo Fisher Scientific RRP4 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–277 of Human RRP4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548446 |
Product Specific Information
- Recommended positive controls: A549, HeLa, HepG2, HCT116
- Predicted reactivity: Mouse (96%), Rat (96%), Zebrafish (80%), Xenopus laevis (84%), Chicken (90%), Bovine (96%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
RRP4 is a non-catalytic component of the RNA exosome complex, which exhibits 3’→5’ exoribonuclease activity and participates in numerous RNA processing and degradation events.
In the nucleus, the RNA exosome complex contributes to maturation of stable RNA species (rRNA, snRNA, snoRNA), elimination of RNA processing by-products, and degradation of defective mRNAs.
In the cytoplasm, it is involved in mRNA turnover, degradation of AU-rich element (ARE)-containing transcripts, and RNA surveillance to prevent translation of aberrant mRNAs.
The complex may also play roles in Ig class switch recombination (CSR) and somatic hypermutation (SHM).
[UniProt]
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.