Thermo Fisher Scientific NPY Monoclonal Antibody (8)
Neuropeptide Y를 검출하는 mouse monoclonal antibody로, 인간 및 설치류 시료에 반응합니다. ELISA, IHC(P), ICC/IF 등 다양한 응용에 적합합니다. Protein A로 정제된 액상 형태이며, 4°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent | - |
| Immunohistochemistry (Frozen) (IHC (F)) | - | 1 publication |
| Immunohistochemistry - Free Floating (IHC (Free)) | - | 1 publication |
| Immunocytochemistry (ICC/IF) | 5 µg/mL | - |
| ELISA | Assay-dependent | - |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Pig |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 8 |
| Immunogen | Synthetic peptide made to human/rat NPY (amino acids 1–97) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1077304 |
Product Specific Information
ABS 028-08-02 detects Neuropeptide Y in human and rat samples.
It has been successfully used in ELISA and immunohistochemistry (paraffin) procedures.
Note: Concentration is lot-dependent and can vary from 0.85–1.15 mg/mL.
Target Information
This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function.
The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase, regulate intracellular calcium levels, and activate potassium channels.
A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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