Thermo Fisher Scientific Peroxiredoxin-3 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Application Note: For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
• Based on 100% sequence identity, this antibody is predicted to react with Orangutan

Target Information

Peroxiredoxin (Prx) is a growing peroxidase family involved in cell proliferation, differentiation, and apoptosis. Mammalian Prxs consist of six members grouped into typical 2-Cys, atypical 2-Cys, and 1-Cys Prx.

• Prx VI belongs to the 1-Cys subgroup, while other 2-Cys Prx isotypes exhibit thioredoxin-dependent peroxidase (TPx) activity.
• Mammalian Prxs are 20–30 kDa in size and vary in localization:
  • Prx I, II, and VI in cytosol
  • Prx III in mitochondria
  • Prx IV in ER and secretion
  • Prx V distributed in peroxisome, mitochondria, and cytosol

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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