Thermo Fisher Scientific ITK Polyclonal Antibody
ITK 단백질을 표적으로 하는 Thermo Fisher Scientific사의 goat polyclonal antibody. Western blot, ICC/IF, Flow cytometry 등에 사용 가능. Human 반응성, mouse 예측 반응성. 액상 형태로 제공되며 -20°C에서 보관.
- 카탈로그번호
- PA517957
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific ITK Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–3 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (RLLRQLAEIAESGL) corresponding to the C-terminus amino acids of ITK (aa 607–620) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10981565 |
Product Specific Information
- This antibody is predicted to react with mouse based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 2,000.
Target Information
ITK is a tyrosine kinase expressed in T-cells which contains both SH2 and SH3 domains. ITK plays a role in T-cell proliferation and differentiation.
The Tec family of non-receptor tyrosine kinases includes Tec, Itk (also known as Emt or Tsk), Btk, Bmx, Txk (Rlk), and Dsrc28C. All members contain SH3 and SH2 domains, and most also have pleckstrin homology (PH) and Tec homology (TH) domains in their amino termini.
Itk associates with CD28 and becomes activated subsequent to CD28 ligation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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