Thermo Fisher Scientific Rhotekin Monoclonal Antibody (OTI2E9)
Rhotekin 단백질을 인식하는 Mouse Monoclonal Antibody (Clone OTI2E9). Western blot, IHC(P), IP에 사용 가능. Human에 반응하며, Affinity Chromatography로 정제됨. PBS 기반 보존 용액에 포함되어 안정적인 저장 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000 | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 | - |
| Immunoprecipitation (IP) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Dog |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E9 |
| Immunogen | Full length human recombinant protein of RTKN produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725236 |
Target Information
This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. It may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP.
Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth, and transformation.
Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer.
Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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