Thermo Fisher Scientific IGF2BP2 Polyclonal Antibody
Thermo Fisher Scientific의 IGF2BP2 Polyclonal Antibody는 인간 IGF2BP2 단백질을 인식하는 토끼 유래 IgG 항체로, WB, IHC, IP 등 다양한 응용에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 4°C에서 보관. 연구용으로만 사용.
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Thermo Fisher Scientific IGF2BP2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 150 and 200 of human Insulin-Like Growth Factor 2 mRNA Binding Protein 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC: Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections
- Based on sequence identity, predicted to react with Orangutan
Target Information
IGF2BP2 is a member of the IGF-II mRNA-binding protein (IMP) family that recruits target transcripts to cytoplasmic protein-RNA complexes. The protein contains four KH domains and two RRM domains, functioning by binding to the 5′ UTR of insulin-like growth factor 2 (IGF2) mRNA and regulating its translation. Alternate splice variants encoding different isoforms have been characterized. Autoantibodies against IGF2BP2 are detected in sera from some patients with hepatocellular carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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