Thermo Fisher Scientific Ankyrin G Polyclonal Antibody
Rabbit polyclonal antibody recognizing human Ankyrin G (ANK3) protein. Validated for WB and ICC/IF applications. Supplied as liquid in PBS with 40% glycerol. Suitable for research use only.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ANK3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790574 |
Product Specific Information
Immunogen sequence:
ENNVFHDPVD GWQNETSSGN LESCAQARRV TGGLLDRLDD SPDQCRDSIT SYLKGEAGKF EANGSHTEIT PEAKTKSYFP ESQNDVGKQ
Target Information
Ankyrin-G is found in several tissues including the brain, where it is expressed as two different isoforms due to tissue-specific RNA processing. These isoforms localize to axon initial segments and nodes of Ranvier. Ankyrin-G is also present at epithelial cell-cell contact sites and in intracellular membranes. It contains a unique serine/threonine-rich sequence following a globular head domain and is thought to play a role in maintaining and targeting ion channels and cell adhesion molecules to the nodes of Ranvier and axon initial segments.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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