Thermo Fisher Scientific cAMP Polyclonal Antibody
Thermo Fisher Scientific의 cAMP Polyclonal Antibody는 인간 Cathelicidin 단백질을 인식하는 Rabbit IgG 항체입니다. Western blot 및 IHC(P)에서 검증되었으며, 고순도 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,500–1:5,000 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human Cathelicidin. Recombinant protein control fragment (Product #RP-90388) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856398 |
Product Specific Information
Immunogen sequence:
RSSDANLYRL LDLDPRPTMD GDPDTPKPVS FTVKETVCPR TTQQSPEDCD FKKDGLVKRC MGTVTLNQAR GSFDISCDKD NKRFALLGDF FRKSKEKIGK EFKRIVQRIK DFLRNLVPR
Target Information
Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis, and neutrophils.
Cathelicidins are a family of antimicrobial peptides characterized by conserved pro-peptide sequences identified in epithelial tissues and some myeloid cells of humans and animals.
LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells.
These molecules are essential for defense against invasive bacterial infection in skin and also play roles in innate and adaptive immunity, including endotoxin neutralization, angiogenesis, wound healing, and immune cell recruitment.
Cathelicidin antimicrobial peptides are potential prototypes for innovative drugs aimed at infection treatment and immune modulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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