Thermo Fisher Scientific Tetanus Toxin Light Chain Polyclonal Antibody
클로스트리디움 테타니 유래 테타누스 톡신 라이트 체인에 특이적인 폴리클로날 항체로, IHC, ICC/IF, ELISA 등 다양한 응용에 적합합니다. Rabbit IgG 형식이며 Protein A로 정제된 액상 제품으로, 연구용으로만 사용됩니다.
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Thermo Fisher Scientific Tetanus Toxin Light Chain Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:5,000–1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bacteria |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from Clostridium tetani E88 Tetanus toxin light chain |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized, and moves by retrograde transport up the axon into the spinal cord, where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the 76-Gln-|-Phe-77 bond of synaptobrevin-2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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