Thermo Fisher Scientific NGB Polyclonal Antibody
Human NGB 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 실험에 최적화되어 있습니다. 항원 친화 크로마토그래피로 정제되었으며, 고순도 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1:20–1:50
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NGB. Recombinant protein control fragment (Product # RP-104249) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2644654 |
Product Specific Information
Immunogen sequence:
PEPELIRQSW RAVSRSPLEH GTVLFARLFA LEPDLLPLFQ YNCRQFSSPE DCLSSPEFLD HIRKVMLVID AA
Highest antigen sequence identity to the following orthologs:
- Mouse: 94%
- Rat: 93%
Target Information
Globins are a superfamily of gas-binding heme proteins present in bacteria, protists, fungi, plants, and animals. They have diverse roles such as binding, transport, scavenging, detoxification, and sensing of gases like oxygen, nitric oxide, and carbon monoxide.
Neuroglobin (Ngb) is a hexacoordinate hemoglobin predominantly expressed in the vertebrate brain, potentially enhancing oxygen supply to neural tissues. Ngb exhibits high oxygen affinity and may participate in neuronal responses to hypoxia or ischemia. In vitro studies show that neuronal hypoxia elevates neuroglobin levels, improving neuronal survival. The human neuroglobin gene is located on chromosome 14q24 and encodes a 151 amino acid protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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