Thermo Fisher Scientific PREX2 Polyclonal Antibody
Human PREX2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. 면역조직화학(IHC) 등에 적합하며, 항원 친화 크로마토그래피로 정제됨. 액상 형태로 4°C 단기, -20°C 장기 보관 가능. 연구용으로만 사용.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P))
Tested Dilution: 1:1,000–1:2,500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PREX2. Recombinant protein control fragment (Product #RP-90632) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2645935 |
Product Specific Information
Immunogen sequence:
GLGFQIRGFG PSVVHAVGRG TVAAAAGLHP GQCIIKVNGI NVSKETHASV IAHVTACRKY RRPTKQDSIQ WVYNSIESAQ EDLQKSHSKP PGDEAGDAFD CKVEEVIDKF NTMAIIDGKK EHVSLTVDNV HLEYGVVYEY DSTAGIKCNV
Highest antigen sequence identity to the following orthologs:
- Mouse: 94%
- Rat: 93%
Target Information
Functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. Mediates the activation of RAC1 in a PI3K-dependent manner. May be an important mediator of Rac signaling, acting directly downstream of both G protein-coupled receptors and phosphoinositide 3-kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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