Thermo Fisher Scientific Calpain S1 Polyclonal Antibody
Calpain S1 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, IHC, ICC/IF, IP 등에 사용 가능. Human 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. E. coli 유래 Human Calpain S1 fragment로 면역화됨. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| Immunoprecipitation (IP) | 1–5 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived Human Calpain S1/CAPNS1 fragment |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography, Protein A |
| Storage Buffer | PBS, pH 7 |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2902439 |
Target Information
Calpains are a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. They are implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress.
Calpain I and II are heterodimeric enzymes with distinct large subunits associated with a common small subunit, each encoded by different genes.
Calpain S1 is the small subunit common to both calpain I and II and is associated with myotonic dystrophy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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