Thermo Fisher Scientific KChIP2 Polyclonal Antibody
KChIP2 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot과 IHC에 적합하며 인간 및 생쥐 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공. 연구용 전용 제품.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.06 µg/mL
- Publications: View 1 publication
Immunohistochemistry (IHC)
- Tested Dilution: 5 µg/mL
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human KCNIP2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2577027 |
Product Specific Information
Peptide sequence:
QLTDSVDDEF ELSTVCHRPE GLEQLQEQTK FTRKELQVLY RGFKNPGALS
Sequence homology:
Cow: 100%
Dog: 86%
Guinea Pig: 100%
Horse: 100%
Human: 100%
Mouse: 93%
Rabbit: 100%
Rat: 100%
Zebrafish: 100%
Target Information
Voltage-gated potassium (Kv) channels are key components of potassium currents in the heart and central nervous system.
In the heart, Kv4 channels are involved in the repolarization phase of the action potential.
In the brain, these channels prevent reverse-propagation of action potentials.
Found associated with Kv4 channels are calcium-binding proteins termed KChIPs (Kv channel interacting proteins).
KChIPs bind to the cytoplasmic amino termini of Kv4 alpha-subunits and modulate their function.
Known KChIPs:
- KChIP1: Expressed in the brain
- KChIP2: Expressed in the brain, heart, and lung; three isoforms (a, b, c)
- KChIP3: Also known as calsenilin and DREAM; expressed in the brain and testis
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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