Thermo Fisher Scientific RORC Monoclonal Antibody (OTI3C12), TrueMAB
Human RORC 단백질(aa 1-266)에 특이적인 Mouse monoclonal antibody. Western blot에 1:2,000 희석으로 사용 가능. Affinity chromatography로 정제된 액상 제품으로, PBS/BSA/glycerol buffer에 보관. -20°C에서 냉동 보관하며, 연구용으로만 사용.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–266 of human RORC produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
ROR gamma is a 560 amino acid DNA-binding transcription factor belonging to the ROR/RZR orphan nuclear receptor subfamily. Reports suggest that ROR gamma is a ligand-activated transcription factor essential for lymphoid organogenesis (lymph nodes and Peyer’s patches) and plays a regulatory role in apoptosis during thymopoiesis. It inhibits the expression of Fas ligand and IL2 and directs differentiation of proinflammatory IL-17+ T helper cells. ROR gamma shares 50–51% sequence identity with RORA and RORB, and is 88% identical to mouse ROR gamma. It is highly expressed in skeletal muscle and at lower levels in various other tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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