Thermo Fisher Scientific MYCN Monoclonal Antibody (OTI2E5), TrueMAB
Human MYCN 단백질(aa 229-464)에 특이적인 Mouse IgG1 단클론 항체. Western blot에 1:500 희석으로 검증됨. 액상 형태, 1 mg/mL 농도, PBS/BSA/glycerol 버퍼에 저장. Neuroblastoma 연구용으로 적합.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 229–464 of human MYCN produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
N-Myc protein is a member of the MYC family of transcription factor proteins with a basic helix-loop-helix (bHLH) domain. N-Myc is similarly regulated and functionally complementary to C-Myc in various cellular growth and differentiation processes.
Amplification and overexpression of the MYCN proto-oncogene occur in approximately 20% of neuroblastomas and are associated with advanced stage disease, rapid tumor progression, and poor prognosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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