Thermo Fisher Scientific ADSL Recombinant Rabbit Monoclonal Antibody (001)
Thermo Fisher Scientific의 ADSL Recombinant Rabbit Monoclonal Antibody (Clone 001)은 인간 ADSL 단백질을 특이적으로 인식하는 고순도 단일클론 항체입니다. ELISA 등에 적합하며, HEK293 세포에서 발현된 recombinant 형태로 제작되었습니다. 연구용으로만 사용됩니다.
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Applications
- ELISA (ELISA)
Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 001 |
| Immunogen | Recombinant Human ADSL / Adenylosuccinate Lyase protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2912194 |
Product Specific Information
Specificity: Human ADSL / Adenylosuccinate Lyase
Target Information
ADSL (adenylosuccinate lyase), also known as AMPS, ASL or ASASE, is a 484 amino acid protein involved in purine biosynthesis and AMP formation from inosine monophosphate. It catalyzes two key reactions in AMP biosynthesis:
- Removal of fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to yield aminoimidazole carboxamide ribotide (AICA).
- Removal of fumarate from adenylosuccinate to yield AMP.
Defects in the ADSL gene cause adenylosuccinase deficiency, an autosomal recessive disorder characterized by epilepsy, growth retardation, and muscular wasting. Multiple isoforms exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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