Thermo Fisher Scientific CSTA Monoclonal Antibody (4D8)
Thermo Fisher Scientific의 CSTA Monoclonal Antibody (4D8)는 사람 단백질 Cystatin A를 인식하는 Mouse IgG2a 항체로, Western blot 및 ELISA에 최적화되어 있습니다. 고순도 Affinity chromatography로 정제된 액상 형태이며, 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 3 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4D8 |
| Immunogen | CSTA (AAH10379, 1–98 a.a) full-length recombinant protein with GST tag (MW of GST tag alone: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MIPGGLSEAK PATPEIQEIV DKVKPQLEEK TNETYGKLEA VQYKTQVVAG TNYYIKVRAG DNKYMHLKVF KSLPGQNEDL VLTGYQVDKN KDDELTGF
Target Information
The cystatin superfamily encompasses proteins containing multiple cystatin-like sequences. Some members act as cysteine protease inhibitors, while others have lost or never acquired this activity.
There are three inhibitory families in the superfamily: type 1 cystatins (stefins), type 2 cystatins, and kininogens.
This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and cathepsins B, H, and L.
The protein is a precursor of the cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance.
Stefins have been proposed as prognostic and diagnostic tools for cancer.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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