Thermo Fisher Scientific PDE4D Polyclonal Antibody
PDE4D 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간 및 랫트 시료에 반응합니다. Western blot 및 ELISA에 적합하며 고순도 Affinity Chromatography로 정제되었습니다. PBS/glycerol buffer에 보관하며 연구용으로 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
ELISA
- Tested Dilution: 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 249–518 of human PDE4D (NP_0011841521) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.43 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2805639 |
Product Specific Information
Immunogen sequence:
FKLLQEENCD IFQNLTKKQR QSLRKMVIDI VLATDMSKHM NLLADLKTMV ETKKVTSSGV LLLDNYSDRI QVLQNMVHCA DLSNPTKPLQ LYRQWTDRIM EEFFRQGDRE RERGMEISPM CDKHNASVEK SQVGFIDYIV HPLWETWADL VHPDAQDILD TLEDNREWYQ STIPQSPSPA PDDPEEGRQG QTEKFQFELT LEEDGESDTE KDSGSQVEED TSCSDSKTLC TQDSESTEIP LDEQVEEEAV GEEEESQPEA CVIDDRSPDT
Positive Samples: HT-29, A-549, SW480
Cellular Location: Apical cell membrane, Cytoplasm, Membrane, Centrosome, Cytoskeleton, Microtubule organizing center
Target Information
This gene encodes one of four mammalian counterparts to the fruit fly dunce gene. The encoded protein has 3’,5’-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-89542_PDE4D_Q08499-1_Rabbit.svg, PA5-89542_PDE4D_Q08499-1_Rabbit_PDP.jpeg)
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