Thermo Fisher Scientific ABCB1 Monoclonal Antibody (OTI2G4), TrueMAB
Human ABCB1 단백질에 특이적인 마우스 단클론 항체로, Western blot에 최적화됨. ATP-binding cassette 수송체 연구에 적합. 액상 형태, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용 가능.
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Thermo Fisher Scientific ABCB1 Monoclonal Antibody (OTI2G4), TrueMAB
Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2G4 |
| Immunogen | Human recombinant protein fragment (aa 347–710 of human ABCB1, produced in SF9 cell) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The membrane-associated protein encoded by ABCB1 is a member of the ATP-binding cassette (ABC) transporter superfamily. These proteins transport various molecules across cellular membranes and are divided into seven subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).
ABCB1 belongs to the MDR/TAP subfamily, which is involved in multidrug resistance. It functions as an ATP-dependent efflux pump for xenobiotic compounds, contributing to decreased drug accumulation and resistance to anticancer drugs. Additionally, it acts as a transporter in the blood-brain barrier.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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