Thermo Fisher Scientific KCNQ2 Polyclonal Antibody
KCNQ2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 인간 KCNQ2 중간 영역을 기반으로 제작되었으며, 다양한 종에서 높은 상동성을 보입니다. 액상 형태로 제공되며, -20°C에서 보관합니다.
- 카탈로그번호
- PA568676
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1.0 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human KCNQ2 (aa 182–231) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2690232 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 93%
Target Information
KCNQs are members of the voltage-dependent non-inactivating potassium channel family. Currently there are five known KCNQs (KCNQ1–5) found in the central nervous system. KCNQ2 and KCNQ3 are important for M-current activation. Studies have shown that KCNQ2 and KCNQ3 form heteromultimers that substantially increase the M-current. Inhibition of M-current controls neuron excitability throughout the nervous system and responsiveness to synaptic inputs. Genetic mutations in these proteins have been linked to disorders such as benign familial neonatal convulsions (BFNC), deafness, neuropathic pain, and epilepsy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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