Thermo Fisher Scientific Fentanyl Monoclonal Antibody (5D8)
Fentanyl 단백질을 인식하는 Mouse monoclonal antibody (Clone 5D8). IHC, ELISA, Lateral Flow 등 다양한 응용에 사용 가능. Protein G로 정제된 액상 항체로, 6.1 mg/mL 농도. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution | Notes |
|---|---|---|
| Immunohistochemistry (IHC) | Assay-dependent | |
| ELISA | 1:5,000 | |
| Lateral Flow (LF) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chemical |
| Host / Isotype | Mouse / IgG |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 5D8 |
| Immunogen | Conjugate of FT hapten and KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 6.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_3090315 |
Product Specific Information
Antibody tested in indirect ELISA.
Target Information
Fentanyl is a synthetic, lipophilic phenylpiperidine opioid agonist with analgesic and anesthetic properties. It selectively binds to the mu-receptor in the central nervous system (CNS), mimicking the effects of endogenous opiates. Activation of the mu-opioid receptor inhibits adenylate cyclase, reducing intracellular cAMP and neurotransmitter release (substance P, GABA, dopamine, acetylcholine, noradrenaline). The analgesic effect is associated with its metabolite morphine, which modulates potassium and calcium channels, leading to neuronal hyperpolarization and reduced excitability.
Source: National Center for Biotechnology Information. PubChem Compound Database; CID=3345.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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