Thermo Fisher Scientific NCAPH2 Polyclonal Antibody
Thermo Fisher Scientific의 NCAPH2 Polyclonal Antibody는 인간 NCAPH2 단백질을 인식하는 토끼 유래 IgG 항체로, WB 및 ICC/IF에 사용됩니다. 고순도 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 안정적 저장이 가능합니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human NCAPH2. Recombinant protein control fragment (Product #RP-105440) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663663 |
Product Specific Information
Immunogen sequence:
AAKLQDFHQWY LAAYADHADS RRLRRKGPSF ADMEVLYWTH VKEQLETLRK LQRREVAEQW LRPAEEDHLE DSLEDLGAAD DFLEPEEYME PEG
Highest antigen sequence identity to the following orthologs:
- Mouse: 70%
- Rat: 69%
Target Information
Structural maintenance of chromosomes (SMC) and non-SMC condensin proteins associate into complexes implicated in chromosome condensation. Proper segregation of replicated sister chromatids requires chromosome condensation prior to metaphase.
Condensin I complex: SMC2, SMC4, CAP-H, CAP-G, CAP-D2
Condensin II complex: SMC2, SMC4, CAP-G2, CAP-H2, CAP-D3
CAP-H2 (NCAPH2, kleisin beta isoform 2) is part of the non-SMC regulatory subcomplex that activates SMC ATPases and promotes mitosis-specific chromatin binding. Individual functions of each non-SMC protein remain to be determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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