Thermo Fisher Scientific CELSR1 Polyclonal Antibody
CELSR1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot과 IHC(Paraffin) 실험에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. 인간 시료 반응성이 있으며, 액상 형태로 -20°C에서 보관합니다.
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- PA599886
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Thermo Fisher Scientific CELSR1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CELSR1 (Accession Q9NYQ6), corresponding to amino acid residues F931–A981 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818819 |
Product Specific Information
Antibody detects endogenous levels of total CELSR1.
Target Information
CELSR1 is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic type cadherins that do not interact with catenins. These cadherins are located at the plasma membrane and contain nine cadherin domains, seven EGF-like repeats, and two laminin A G-type repeats in their ectodomain. They possess seven transmembrane domains, unique to this subfamily. CELSR1 proteins are thought to function as receptors in contact-mediated communication, with cadherin domains acting as homophilic binding regions and EGF-like domains facilitating cell adhesion and receptor-ligand interactions. This gene is developmentally regulated and neural-specific, playing a role in early embryogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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