Thermo Fisher Scientific GLRX2 Polyclonal Antibody
Human GLRX2 단백질을 인식하는 Rabbit Polyclonal Antibody로, ICC/IF에 적합합니다. Antigen affinity chromatography로 정제되었으며, PBS buffer(40% glycerol, 0.02% sodium azide) 상태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human GLRX2. Recombinant protein control fragment (Product #RP-106759) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664913 |
Product Specific Information
Immunogen sequence:
AAASGMESNTS SSLENLATAP VNQIQETISD NCVVIFSKTS CSYCTMA
Highest antigen sequence identity to the following orthologs:
- Mouse: 73%
- Rat: 73%
Target Information
Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase. Grxs form part of the glutaredoxin system, comprising NADPH, GSH, and glutathione reductase, which transfers electrons from NADPH to glutaredoxins via GSH.
First discovered in E. coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxidoreductase via two redox-active cysteine residues.
The active sequence (Cys-Pro-Tyr-Cys) is conserved across various species. The 12-kD dithiol protein plays a role in the reduction of mixed disulfides in cells exposed to oxidative stress.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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