Thermo Fisher Scientific SORL1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 2065-2214 of human SORL1 (NP_0030961) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:SORL1,uniProtId:Q92673-1,ncbiNodeId:9606,antigenRange:2065-2214,antigenLength:2214,antigenImageFileName:PA5-88941_SORL1_Q92673-1_Rabbit.svg,antigenImageFileNamePDP:PA5-88941_SORL1_Q92673-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.93 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805239

Product Specific Information

Immunogen sequence: DSAMNITAYL GNTTDNFFKI SNLKMGHNYT FTVQARCLFG NQICGEPAIL LYDELGSGAD ASATQAARST DVAAVVVPIL FLILLSLGVG FAILYTKHRR LQSSFTAFAN SHYSSRLGSA IFSSGDDLGE DDEDAPMITG FSDDVPMVIA; Positive Samples: SH-SY5Y, HepG2; Cellular Location: Endosome, Golgi apparatus, Membrane, Single-pass type I membrane protein

Target Information

This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 domain-containing receptor family, and the low density lipoprotein receptor family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded protein is translated as a preproprotein and likely plays roles in endocytosis and sorting. There may be an association between expression of this locus and Alzheimer`s Disease.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.