Thermo Fisher Scientific BAG5 Polyclonal Antibody
Human BAG5 단백질을 인식하는 Goat Polyclonal Antibody로 Western blot 및 IHC(P) 실험에 적합. 고순도 액상 제형으로 안정적인 신호 검출 제공. TBS buffer에 0.5% BSA 및 sodium azide 포함, -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 3.75 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence DMGNQHPSISRLQ-C (aa 2–14) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2932669 |
Product Specific Information
- Variants (NP_004864.1; NP_001015048.1) encode the same isoform.
- Tested in Peptide ELISA: antibody detection limit dilution 1:64,000.
Target Information
It has been hypothesized that the BAG-5 protein induces the death of nigral neurons through its predicted interaction with hsp70, leading to increased protein aggregation and cell death by disinhibition of hsp70’s anti-apoptotic function.
BAG-5 is believed to play an important role in neuronal death mechanisms.
It may also act as a modulator of the hsp70/hsp40 chaperone axis or coordinate localization/modulation of other BAG-containing proteins via BAG–BAG heterodimerization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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