Thermo Fisher Scientific VPS4B Polyclonal Antibody
Thermo Fisher Scientific의 VPS4B Polyclonal Antibody는 인간 VPS4B 단백질을 인식하는 토끼 다클론 항체입니다. IHC(P)에서 1:50–1:200 희석으로 사용 가능하며, 항원 친화 크로마토그래피로 정제되었습니다. 단기 4°C, 장기 -20°C 보관을 권장합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human VPS4B. Recombinant protein control fragment (Product #RP-104038) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2649474 |
Product Specific Information
- Immunogen sequence: AQKPVKEGQP SPADEKGNDS DGEGESDDPE
- Antigen sequence identity: Mouse - 80%, Rat - 77%
Target Information
The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities) and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. These paralogs share a high degree of amino acid sequence similarity with each other and with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with endosomal compartments and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the other resides on chromosome 16.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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