Thermo Fisher Scientific DNase II Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human DNASE2. Recombinant protein control fragment (Product #RP-103624). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DNase II,uniProtId:O00115-1,ncbiNodeId:9606,antigenRange:266-356,antigenLength:360,antigenImageFileName:PA5-84716_DNase_II_O00115-1_Rabbit.svg,antigenImageFileNamePDP:PA5-84716_DNase_II_O00115-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2791867

Product Specific Information

Immunogen sequence: NCSDIWQVLN VNQIAFPGPA GPSFNSTEDH SKWCVSPKGP WTCVGDMNRN QGEEQRGGGT LCAQLPALWK AFQPLVKNYQ PCNGMARKPS R

Target Information

DNase II is a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.