Thermo Fisher Scientific EGR2 Polyclonal Antibody, Biotin
EGR2 단백질을 인식하는 Biotin 결합 Rabbit Polyclonal 항체입니다. Western blot, ELISA, Immunoprecipitation에 사용 가능하며, Human, Mouse, Rat 시료에 반응합니다. 고순도 Affinity chromatography 정제, 안정적 보관 가능한 액상 형태입니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide taken within amino acid region 60–150 on mouse E3 SUMO-protein ligase EGR2 |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The EGR2 gene encodes the early growth response 2 protein, a transcription factor that binds to specific DNA regions to regulate gene expression. This protein plays a crucial role in the formation and maintenance of myelin, the protective sheath around nerve cells that ensures efficient nerve impulse transmission.
Mutations in the EGR2 gene are associated with Charcot-Marie-Tooth disease types 1D and 4E, and severe forms such as Dejerine-Sottas syndrome, which can present in infancy or early childhood.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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