Thermo Fisher Scientific C17orf96 Polyclonal Antibody
Human C17orf96 단백질의 C-말단 영역을 타겟으로 한 Rabbit Polyclonal Antibody. Western blot에 최적화되어 있으며, 0.5 mg/mL 농도의 액상 형태로 제공. PBS + sucrose buffer에 보존되며, -20°C에서 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of human C17orf96 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2691012 |
Product Specific Information
This target displays homology in the following species:
- Cow: 86%
- Dog: 93%
- Horse: 93%
- Human: 100%
- Mouse: 79%
- Rat: 79%
Target Information
Elongin BC and Polycomb repressive complex 2-associated protein (EPOP), also known as C17ORF96, is a scaffold protein that bridges the PRC2/EED-EZH2 complex and the elongin BC complex. It fine-tunes transcriptional activity of polycomb group (PcG) target genes in embryonic stem cells (ESCs).
C17ORF96 plays a key role in genomic regions with both active and repressive chromatin properties in pluripotent stem cells, maintaining low-level expression of PcG target genes. It recruits the elongin BC complex to restrict excessive PRC2/EED-EZH2 activity and interacts with USP7 to promote H2B deubiquitination at promoter sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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