Thermo Fisher Scientific BTBD7 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide with sequence ESKLYSLDHGHEKPQ-C (aa 40-54). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BTBD7,uniProtId:Q9P203-1,ncbiNodeId:9606,antigenRange:40-54,antigenLength:1132,antigenImageFileName:PA5-142661_BTBD7_Q9P203-1_Goat.svg,antigenImageFileNamePDP:PA5-142661_BTBD7_Q9P203-1_Goat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Ammonium sulfate precipitation

Storage buffer

TBS, pH 7.3, with 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2933307

Product Specific Information

Additional Information: This antibody is expected to recognize both reported isoforms (NP_001002860.2; NP_060637.1).

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.

Target Information

Acts as a mediator of epithelial dynamics and organ branching by promoting cleft progression. Induced following accumulation of fibronectin in forming clefts, leading to local expression of the cell-scattering SNAIL2 and suppression of E-cadherin levels, thereby altering cell morphology and reducing cell-cell adhesion. This stimulates cell separation at the base of forming clefts by local, dynamic intercellular gap formation and promotes cleft progression. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.