Thermo Fisher Scientific RHEB Recombinant Rabbit Monoclonal Antibody (ARC0827)
RHEB 단백질을 인식하는 토끼 단클론 항체로, 인간 및 마우스 시료에 반응합니다. ICC/IF 및 ELISA에 적합하며, HEK293 세포에서 발현된 재조합 항체입니다. 고순도의 Affinity Chromatography 정제 제품으로, 안정적인 PBS/glycerol 완충액에 보존됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | ARC0827 |
| Immunogen | Synthetic peptide corresponding to amino acids 1–100 of human Rheb (UniProt ID: Q15382) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.63 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol, 0.05% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2849293 |
Product Specific Information
Immunogen sequence:
MPQSKSRKIA ILGYRSVGKS SLTIQFVEGQ FVDSYDPTIE NTFTKLITVN GQEYHLQLVD TAGQDEYSIF PQTYSIDING YILVYSVTSI KSFEVIKVIH
Target Information
Rheb encodes a member of the small GTPase superfamily and produces a lipid-anchored, cell membrane protein containing five repeats of the RAS-related GTP-binding region. This protein is essential for growth and cell cycle regulation via the insulin/TOR/S6K signaling pathway. It exhibits GTPase activity and alternates between GDP- and GTP-bound forms, with farnesylation required for its function. Three pseudogenes have been identified—two on chromosome 10 and one on chromosome 22.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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