Thermo Fisher Scientific MAPK1 Monoclonal Antibody (OTI6F8), TrueMAB
MAPK1(ERK2) 단백질을 인식하는 Mouse IgG2a 단일클론 항체로, WB, IHC, Flow Cytometry, IP에 적합. 고순도 액상형으로 PBS/BSA/glycerol buffer에 보관. 세포 신호전달 및 MAPK 경로 연구용에 최적화.
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Thermo Fisher Scientific MAPK1 Monoclonal Antibody (OTI6F8), TrueMAB
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Flow Cytometry (Flow) | 1:100 |
| Immunoprecipitation (IP) | 2 µg/500 µL |
Publications
- View 2 publications on PubMed
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Dog, Human, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6F8 |
| Immunogen | Full-length human recombinant MAPK1 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats:
Target Information
MAPK1 (ERK2) is a serine/threonine kinase that acts as an important activator of p90 RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway.
MAP kinases (ERKs) serve as integration points for multiple biochemical signals and regulate processes such as proliferation, differentiation, transcription regulation, and development.
Activation occurs through phosphorylation by upstream kinases, after which MAPK1 translocates to the nucleus to phosphorylate nuclear targets.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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