Thermo Fisher Scientific NSUN6 Polyclonal Antibody
Rabbit 폴리클로날 항체로 Human NSUN6 단백질을 인식. Western blot 및 Immunocytochemistry에 최적화된 연구용 시약. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성 제공. 세포 내 RNA 메틸화 연구 및 골전이 관련 연구에 활용 가능.
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Thermo Fisher Scientific NSUN6 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 179–469 of NSUN6 (Uniprot ID: Q8TEA1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.84 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris Glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11153931 |
Product Specific Information
- Recommended positive controls: 293T, HeLaS3, HepG2, Molt-4
- Predicted reactivity: Mouse (82%), Rat (81%), Bovine (90%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
NSUN6 is an RNA methyltransferase that catalyzes methylation at cytosine C72 in specific tRNAs. It localizes mainly in the cytoplasm and colocalizes with the Golgi apparatus and pericentriolar matrix, suggesting its role in late tRNA biogenesis. NSUN6 may also play a key role in bone metastasis and represents a potential therapeutic target.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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