Thermo Fisher Scientific Human SR-BI Synthetic Peptide
인간 SCARB1의 아미노 말단 부위 15개 아미노산으로 구성된 합성 펩타이드. 항체 PA5-20756과 함께 차단 실험에 사용 가능. HDL 관련 콜레스테롤 대사 연구에 적합. 액상 형태, 200 µg/mL 농도, -20°C 보관.
- 카탈로그번호
- PEP0870
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids near the amino terminus of human SCARB1.
PEP-0870 can be used as a blocking peptide with polyclonal antibody PA5-20756.
Target Information
High density lipoproteins (HDLs) play a critical role in cholesterol metabolism and their plasma concentrations are inversely correlated with risk for atherosclerosis. The SR-BI binds HDLs and mediates selective uptake of HDL cholesteryl ester. SR-BI binds HDL with high affinity, is expressed primarily in liver and nonplacental steroidogenic tissues, and mediates selective cholesterol uptake by a distinct mechanism. In mice, SR-BI plays a key role in determining plasma lipoprotein cholesterol levels and cholesterol storage in the adrenal gland.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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