Thermo Fisher Scientific GRB7 Monoclonal Antibody (3C12)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

10 µg/mL

-

Immunoprecipitation (IP)

1-5 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2b, lambda

Class

Monoclonal

Type

Antibody

Clone

3C12

Immunogen

GRB7 (AAH06535, 37 a.a. approximately 136 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GRB7,uniProtId:Q14451-1,ncbiNodeId:9606,antigenRange:37-136,antigenLength:532,antigenImageFileName:H00002886-M03_GRB7_Q14451-1_House_mouse.svg,antigenImageFileNamePDP:H00002886-M03_GRB7_Q14451-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: EEVKRSQPLL IPTTGRKLRE EERRATSLPS IPNPFPELCS PPSQSPILGG PSSARGLLPR DASRPHVVKV YSEDGACRSV EVAAGATARH VCEMLVQRAH

Target Information

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with epidermal growth factor receptor (EGFR) and ephrin receptors. The protein plays a role in the integrin signaling pathway and cell migration by binding with focal adhesion kinase (FAK). Alternative splicing results in multiple transcript variants encoding different isoforms, although the full-length natures of only two of the variants have been determined to date.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.