
Thermo Fisher Scientific DUOX1 Polyclonal Antibody
DUOX1 단백질에 특이적인 Rabbit Polyclonal 항체로 Western blot 및 IHC(Paraffin) 실험에 적합. Human에 반응하며 Mouse, Rat, Dog, Pig, Bovine에 예측 반응. 항원 친화 크로마토그래피로 정제된 액상 항체로, PBS/glycerol buffer에 보존.
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- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human DUOX1. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2792592 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (89%), Rat (87%), Dog (86%), Pig (90%), Bovine (90%).
- Positive Control: A549, H1299, HCT116, unboiled A431, A431 membrane extract.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX2. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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