Thermo Fisher Scientific TMEM245 Polyclonal Antibody
TMEM245 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P) 및 ICC/IF에 적합합니다. 인간 시료 반응성이 있으며, 항원 친화 크로마토그래피로 정제되었습니다. PBS(40% glycerol) 완충액에 보관되며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:2,500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TMEM245. Recombinant protein control fragment (Product #RP-92899) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648672 |
Product Specific Information
Immunogen sequence:
AELPGQVISM AASTLANLAI SITGYESSSE DQPSTQPAEA VDRGESAPTL STSPSPSSPS PTSPSPTLGR RRPEIGTFLR KKK
Antigen sequence identity:
Mouse – 79%, Rat – 79%
Target Information
C9orf5 (chromosome 9 open reading frame 5), also known as CG2, is a 911 amino acid multi-pass membrane protein widely expressed and exists as four alternatively spliced isoforms.
The gene encoding C9orf5 maps to human chromosome 9, which consists of about 145 million bases, represents 4% of the human genome, and encodes nearly 900 genes.
Chromosome 9 is associated with several genetic phenomena and diseases:
- Deletion of distal 9p can cause male-to-female sex reversal.
- Hereditary hemorrhagic telangiectasia is linked to the ENG gene on chromosome 9.
- Familial dysautonomia is associated with the IKBKAP gene.
- Chromosome 9 contains the largest interferon gene cluster.
- It partners with chromosome 22 in the BCR-ABL translocation found in leukemias.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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