
Thermo Fisher Scientific TCAP Monoclonal Antibody (OTI11H10)
TCAP 단백질을 인식하는 Mouse 모노클로날 항체로, Western blot 및 IHC(P)에서 검증됨. 인간 시료 반응성, 비결합형 액상 형태, 높은 순도의 Affinity Chromatography 정제. 근육 단백질 titin 관련 연구에 적합.
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Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI11H10 |
| Immunogen | Full length human recombinant protein of TCAP produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725484 |
Target Information
Sarcomere assembly is regulated by the muscle protein titin, a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold for myofibrils and other muscle-related proteins.
TCAP is found in striated and cardiac muscle, binding to titin Z1-Z2 domains and acting as a substrate of titin kinase—interactions critical for sarcomere assembly.
Mutations in the TCAP gene are associated with limb-girdle muscular dystrophy type 2G.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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