Thermo Fisher Scientific TCAP Monoclonal Antibody (OTI11H10)

Applications

• Western Blot (WB): 1:2,000
• Immunohistochemistry (Paraffin) (IHC (P)): 1:150

Product Specifications

Target Information

Sarcomere assembly is regulated by the muscle protein titin, a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold for myofibrils and other muscle-related proteins.
TCAP is found in striated and cardiac muscle, binding to titin Z1-Z2 domains and acting as a substrate of titin kinase—interactions critical for sarcomere assembly.
Mutations in the TCAP gene are associated with limb-girdle muscular dystrophy type 2G.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.

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