Thermo Fisher Scientific CTSL1 Monoclonal Antibody (OTI5C8), TrueMAB
인간 Cathepsin L 단백질을 인식하는 단클론 항체로 Western blot 및 IHC(Paraffin) 실험에 적합합니다. 마우스 IgG1 형식의 TrueMAB 항체로, 액상 형태이며 1 mg/mL 농도로 제공됩니다. -20°C에서 보관하며 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5C8 |
| Immunogen | Human recombinant protein fragment (amino acids 114–333 of human CTSL produced in E. coli) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen, elastin, and alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies, myocardial ischemia, and renal tubular response to proteinuria. This protein, a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains produced from a single precursor. At least two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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