Thermo Fisher Scientific RAB8A Monoclonal Antibody (7G8B11)
RAB8A 단백질을 인식하는 Mouse Monoclonal Antibody로 Western blot, Flow cytometry, ELISA에 적합. Human 시료 반응성, Protein G 정제, 1 mg/mL 농도. 연구용으로 단백질 수송 관련 연구에 활용 가능.
- 카탈로그번호
- MA531883
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Flow Cytometry (Flow) | 1:200–1:400 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7G8B11 |
| Immunogen | Purified recombinant fragment of human Rab8 (AA: 68–207) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C; avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787506 |
Product Specific Information
MA5-31883 has been tested in indirect ELISA.
Target Information
The protein encoded by this gene is a member of the RAS superfamily, consisting of small GTP/GDP-binding proteins (~200 amino acids). RAB/YPT family proteins may play a role in protein transport from the endoplasmic reticulum to the Golgi and plasma membrane.
RAB8A shares 97%, 96%, and 51% similarity with dog RAB8, mouse MEL, and mouse YPT1 respectively, and contains four GTP/GDP-binding sites common to RAS proteins.
It has a C-terminal CAAX motif, typical of RAS superfamily members but absent in YPT1 and most RAB proteins. Although isolated as a transforming gene from a melanoma cell line, no linkage between MEL and malignant melanoma has been demonstrated. This oncogene is located 800 kb distal to MY09B on chromosome 19p13.1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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