Thermo Fisher Scientific CD177 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CD177. Recombinant protein control fragment (Product #RP-106130). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CD177,uniProtId:Q8N6Q3-1,ncbiNodeId:9606,antigenRange:24-118,antigenLength:437,antigenImageFileName:PA5-83827_CD177_Q8N6Q3-1_Rabbit.svg,antigenImageFileNamePDP:PA5-83827_CD177_Q8N6Q3-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2790979

Product Specific Information

Immunogen sequence: CQFGTVQHVW KVSDLPRQWT PKNTSCDSGL GCQDTLMLIE SGPQVSLVLS KGCTEAKDQE PRVTEHRMGP GLSLISYTFV CRQEDFCNNL VNSLP

Target Information

CD177 (NB1/HNA-2a and PRV-1 form) is a GPI-anchored glycoprotein present mainly on neutrophils. Its plasma membrane expression is increased during pregnancy and and inflammation or after G-CSF application. Ligand of CD177 has been identified as CD31 (PECAM-1). CD177 participates in neutrophil transmigration and seems to be also a pro-proliferative molecule. The antibodies against CD177 can be involved in neonatal alloimmune neutropenia (NAN).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.